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Welcome to MethylGene

MethylGene is a biopharmaceutical company with a mission to discover, develop and deliver new drugs to treat cancer. Our goal is to eventually market products that will improve the lives of patients suffering from this disease.

MethylGene 's MGCD0103, an isoform-selective histone deacetylase (HDAC) inhibitor, has been in clinical trials for for solid tumours and hematological malignancies; and MGCD265, our multi-targeted kinase (c-Met) inhibitor has entered a Phase II program for solid tumor cancers and NSCLC. In addition, MGCD290, a Hos2 fungal inhibitor for the treatment of fungal infections, is also in Phase I trials. Please visit our
Clinical Development section for a more detailed list of our programs and our partners.

It takes a combination of intuition, discipline, knowledge and dedicated employees to harness innovation and turn discoveries into drug products. We deliver value through milestone-driven execution, prudent fiscal management and by a grounded approach to our scientific and business activities. This culture pervades MethylGene and we believe it is essential to discovering drugs, building a business and building long-term value for our patients and shareholders.

We appreciate your ongoing support as we work to accomplish our goals. I hope you will take a moment to visit our website and learn more about MethylGene's products and people.

Sincerely,

Donald F. Corcoran
President and CEO








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